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A new analysis method for evaluating bacterial growth with microplate readers

Fig 4

Predictions of the models for the dependence of the cell number n, the number of GFP^f p_f, and their time derivatives on the maximum growth rate k₀.

(A-D) Predicted curves of the models for the (A) n, (B) p_f, (C) dn/dt, and (D) d²p_f/dt² as functions of time with increasing growth rates k₀ ranging from 0.50 to 2.00 hr^-1. (E) Predicted dependence of the peak heights (η_p–black circles and –green triangles) of the dn/dt and d²p_f/dt² curves on the growth rate k₀ in the model. Inset: predicted dependence of the fitted maximum specific growth rate μ on the growth rate k₀ in the model. (F) Predicted dependence of the peak locations (τ_p–black circles and –green triangles) of the dn/dt and d²p_f/dt² curves and the fitted lag time (λ –blue squares) on the growth rate k₀. Blue dashed line and red dotted line are exponential fittings.

doi: https://doi.org/10.1371/journal.pone.0245205.g004