Cortical hemodynamic mapping of subthalamic nucleus deep brain stimulation in Parkinsonian patients, using high-density functional near-infrared spectroscopy
Fig 3
Cortical effects of STN-DBS stimulation in patients performing a motor task in the OFF-stim condition (A: right hand movement; B: left hand movement). Relative changes in cortical [HbO], [HbR], and [HbT] during hand movements in the OFF-stim condition. During movement in OFF-stim condition, an increase in [HbO] and a decrease in [HbR] (neurovascular coupling) were observed over the contralateral SM and PM areas, together with a significant but smaller change in metabolism over the DLPFC area, i.e. a concomitant increase in [HbO], [HbR], and [HbT], indicating cortical activation in the absence of neurovascular coupling.