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Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients

Fig 2

Heat map of inflammatory marker gene expression levels in graft tissue.

The expression of 15 genes coding for 13 inflammatory biomarkers in 30 treated patients (to the left) vs 30 patients in the control group (to the right). Darker color indicates higher expression levels. Z-scores of duplicated genes in the array are averaged. Genes coding for proteins with different nomenclature: ACVR1/ACVR1B/ ACVR1C, activin A receptor subunits; ANGPT2, angiopoietin-2; COL18A1, endostatin; LCN2, neutrophil gelatinase-associated lipocalin (NGAL); LGALS3, galectin-3; TNFRSF11B, osteoprotegerin; TNFRSF1A, soluble tumor necrosis factor receptor-1 (sTNFr1).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0243759.g002