High CSF thrombin concentration and activity is associated with an unfavorable outcome in patients with intracerebral hemorrhage
Fig 1
mRS after ICH is dependent on CSF FIIa and TAT concentrations.
CSF concentrations of FIIa 24h after ICH correlated with the mRS disability index 6 weeks (r = 0.61; p = 0.004) and 6 months (r = 0.57; p = 0.009) after discharge from hospital. Further, the TAT-complex as surrogate parameter of coagulation correlated with the mRS disability index at 6 weeks (r = 0.65; p = 0.013) and 6 months (r = 0.65; p = 0.015).