Oxidative damage to urinary proteins from the GRMD dog and mdx mouse as biomarkers of dystropathology in Duchenne muscular dystrophy
Fig 3
Total protein carbonylation and protein tyrosine modifications (B) in muscle from normal and GRMD dogs (a and b respectively) and C57 and mdx mice (c and d respectively). Asterisks represent significant differences of p<0.05. Data are presented as mean ± SEM and n = 6. All were standardised to total protein. Representative blot images are shown of DNP labelling of several proteins’ bands (a and c) and DiBrY labelling of predominately labelled proteins (b, approximately 50 kDa and d, approximately 25 kDa).