Effects of an anti-IGF-1 receptor monoclonal antibody on laminitis induced by prolonged hyperinsulinaemia in Standardbred horses
Fig 3
Change in the distance between the hoof wall (HW) and the distal phalanx (DP), measured using radiography.
The values represent individual feet (a) or the average for the left and right front foot of each horse (b), belonging to one of three groups treated with: 0.9% saline (negative-control, n = 6, white bars); a combination of insulin and glucose infusion (positive-control, n = 6, grey bars); or a combination of insulin and glucose, plus an anti-IGF-1R monoclonal antibody (mAb11, n = 7, black bars). *P < 0.05 compared with the positive-control group.