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Tuning the size and composition of manganese oxide nanoparticles through varying temperature ramp and aging time

Fig 9

Average cumulative release of Mn2+ from PLGA Mn3O4 (17 nm), PLGA MnO (19 nm), and PLGA MnO (32 nm) NPs after 24 hr of incubation at pH 7.4, pH 6.5, and pH 5.

Mn2+ release was significantly greater from PLGA MnO NPs compared to PLGA Mn3O4 NPs at pH 5. Three different batches of each type of NPs were analyzed during controlled release. Error bars are average ± standard deviation. **p<0.01 was defined as highly significant.

Fig 9

doi: https://doi.org/10.1371/journal.pone.0239034.g009