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Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback

Fig 6

Expression of miR-449a in the anterior pituitary.

Expression of miR-449a in the anterior pituitary of control rats (NBW) or LBW rats exposed to a standard chow (Std.Chow) or high-fat diet (HFD) were quantified. The miRNA expression level is a ratio obtained by correcting the ΔΔCT values of miR-449a with the ΔΔCT values of U6 and setting the value of Std.Chow-fed NBW to 100. n = 7. Statistical analysis was performed using one-way ANOVA followed by Turkey's post hoc test for multiple comparisons.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0238223.g006