Hippocampal subfield volumes in abstinent men and women with a history of alcohol use disorder
Fig 1
Hippocampal subfield segmentation using the procedure by Iglesias and colleagues [6].
A. This three-dimensional model of the left hippocampus depicts its segmentation into 12 subfields (although not all subfields are visible from the angle presented). B. This coronal section through the hippocampus illustrates subfields that are visible in the slice, and it shows the two major hippocampal neural pathways originating in the entorhinal cortex and as described in the text: The yellow arrow shows the direct circuit; the pink arrows indicate the trisynaptic circuit. Although the connection from CA1 to the subiculum is not explicitly part of the trisynaptic circuit, it is important as an output region, in addition to CA1. Abbreviations: CA1 = cornu ammonis 1; CA2+3 = cornu ammonis 2 and 3; CA4 = cornu ammonis 4; DG = dentate gyrus; HATA = hippocampal-amygdaloid transition area; Sub = subiculum.