Cuminaldehyde potentiates the antimicrobial actions of ciprofloxacin against Staphylococcus aureus and Escherichia coli
Fig 2
Cuminaldehyde in vitro effects on S. aureus and E. coli biofilm formation.
Different concentrations of cuminaldehyde (MIC/2-MIC/8) were incubated with S. aureus and E. coli, for 24h. Biofilm viability was assessed Cuminaldehyde effects on the viability and mass of the biofilm formed by S. aureus ATCC 6538 (a and e), EAEC 042 (d and h) and the clinical isolates Saa (b and f) and Sav (c and g) were evaluated. For comparison, ciprofloxacin effects on the viability and mass of the biofilm formed by S. aureus ATCC 6538 (i and m), EAEC 042 (l and p) and the clinical isolates Saa (j and n) and Sav (k and o) were also assessed. Vehicle (2% DMSO in saline)-treated bacteria were used as controls. *p<0.05; differs from the control group. Data were obtained from three independent experiments.