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The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis

Fig 4

Histology of intestine and mesenterium.

4A The mucosa is down at left and the serosa is at right. The serosa shows a rich fibrinopurulent exudate, consistent with peritonitis. Leukocytes between the smooth muscle layers also are visible (AF-16). 4B Mesenterium. Necrosis and intense inflammatory reaction in the fat and connective tissues, consistent with peritonitis (control).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0232302.g004