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The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis

Fig 3

Histology of lung samples, AF-16 vs control.

3A Intense inflammatory cell reaction shows leukocytes rich in polymorphs in the alveoli (down, at left) and in the capillaries in the interlobular septum (AF-16). 3B Bronchial vessel shows leukocytes adhering at the endothelium. It could be an early stage in the process of leukocyte migration through the vessel wall, but leukocytes seem to remain in the intima which is suggestive of endoarteriolitis, which could be predisposing for thrombosis (control).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0232302.g003