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Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

Fig 2

Constructed protein-protein interaction network of 114 downregulated genes in post-treatment versus pre-treatment actinic keratosis samples.

Nodes represent proteins and different line intensities denote the type of evidence for the interaction. Statistical analysis results for the network: number of nodes: 114, number of edges: 355; average node degree: 6.23; average local clustering coefficient: 0.48; expected number of edges: 35; PPI enrichment p-value < 1E-16.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0232146.g002