Inhibiting of self-renewal, migration and invasion of ovarian cancer stem cells by blocking TGF-β pathway
Fig 3
Effect of SB525334 on TGF-β pathway and EMT in CSCs.
(A) mRNA expression (A) and protein expression (B) levels of TGF-β, Smad2, p-Smad2, Smad3, p-Smad3, and Smad4 in CSCs with and without the use of SB525334; (C) mRNA and protein expressions of E-cadherin, Snail and Vimentin in CSCs with and without the use of SB525334; *P <0.05.