Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmdmdx rat model
Fig 3
Anhedonia and anxiety are not affected in Dmdmdx rats at 3 and 7 months.
For WT (black dots, n = 7) and Dmdmdx rats (grey dots, n = 6), (A) Sucrose preference and (B) Water consumption are not affected in dystrophin-deficient rats, neither at 3 months, nor at 7 months, (C) Time spent in the open arm of the elevated plus maze (% of time spent on open and closed arms) is also stable over time in both genotypes, (D) Total number of entries into open and closed arms is significantly lower in Dmdmdx rats. Data are expressed as mean ± SEM. **p < 0.01.