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Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmdmdx rat model

Fig 2

Motor functions impairment in the ledged-beam walking test in Dmdmdx rats at 7 months.

For WT (black dots, n = 8) and Dmdmdx rats (grey dots, n = 10), (A) Time spent to cross the beam was significantly higher in mutant animals, (B) Number of steps was also higher, but without reaching significance, and (C) Number of errors per step was unaffected. Data are expressed as mean ± SEM. *p < 0.05.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0230083.g002