NRF2 deficiency increases obesity susceptibility in a mouse menopausal model
Fig 3
Changes in bodyweight in different groups of mice.
WT-CON: wild-type control, WT-OVX: wild-type ovariectomy, KO-CON: Nrf2−/− control, KO-OVX: Nrf2−/− ovariectomy. (a) The weight gain in different groups of mice preoperatively and at postoperative week 9. *P < 0.05; **P < 0.01. (b). Changes in bodyweight curve of different groups of mice during 9 weeks after ovariectomy. *P < 0.05; **P < 0.01 (KO-OVX vs KO-CON); # P < 0.05; ##P < 0.01 (KO-OVX vs WT-CON). Results are shown as mean ± SEM. Data were analyzed by One-way ANOVA with Bonferroni's Multiple comparison test.