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The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study

Fig 1

Schematic illustration of the study protocol.

The day before scheduled surgery patients completed the Demographic, B-MEPS tool, and Central Sensitization Inventory (CSI). Then, patients underwent a series of experimental pain tests: Pressure pain threshold (PPT), pressure pain tolerance (PPTol) and conditioned pain modulation test (CPM) and blood sample analysis. During postoperative days 1–3 pain-related outcomes were assessed, including postoperative rest pain and movement-evoked pain intensity, and morphine Rehabilitation Questionnaire (QoR-15) was applied on the 3rd day.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0227441.g001