Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cells
Fig 6
The AMPK activator AICAR prevents detrimental effects of palmitate.
Cells were pretreated with AICAR (0.1 or 0.5mM) for 2hr then co-incubated with palmitate (PA). Fold change from control in a) viability and b) apoptosis after treatment with palmitate (PA), AICAR, or a combination of both. Data are expressed as mean±SEM; n = 2–6 independent experiments; *p<0.05 vs control, #p<0.05 vs both PA concentrations.