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Induction of miR 21 impairs the anti-Leishmania response through inhibition of IL-12 in canine splenic leukocytes

Fig 3

Th1 and Th2 profile.

Th1 profile in SL transfected with negative control (scrambled), miR 21 mimic, miR 21 inhibitor and cultured for 67h. (A) SL from dogs with CanL and (B) SL from control non-infected dogs. Data represent the mean values of Th1/Th2 + standard error of the mean. Asterisks represent significance (p<0.05) by Friedman Test with multiple comparison.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0226192.g003