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Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice

Fig 2

Effects of adding DSM, DSM derived microvesicles μV (μV) or media on PCC velocity for mouse jejunal segments, in vitro.

Upper panels: bar graphs showing means and standard errors. c) DSM (N = 20), b) conditioned medium (CM) (N = 28) and d) DSM μV reduced PCC velocity (N = 20). Neither (a) broth (N = 20) nor conditioned medium minus μV (e) (CM-μV) (N = 20) altered PCC velocity. P values derived from paired t-tests are given above horizontal bars. Lower panels: individual value plots of difference (treatment-control Krebs) with 95% confidence intervals for each matching graph in upper row. All subsequent figures show the same relationships between upper and lower panels. Significance determined when p < 0.05.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0225481.g002