Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs
Fig 5
Engrafted biosensor cells have minimal impact on liver functionality.
(A) Lactate, (B) Glucose levels, (C) Oxygen consumption, and (D) AST levels obtained from perfusate samples collected throughout perfusion. Lactate, glucose, and oxygen were measured in real time using a blood chemistry analyzer (i-STAT). (E) Weight of liver measured pre and post perfusion.