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Allele-specific enhancer interaction at the Peg3 imprinted domain

Fig 7

Four different types of the enrichment patterns.

For a given ECR, the enrichment levels representing its potential interaction with the promoters of Peg3 or Zim1 were compared between two alleles, which were summarized with the average values with standard deviations. For a given promoter, the enrichment levels measured from the paternal and maternal alleles were indicated with blue and red bars. The values for the paternal and maternal alleles of Peg3 were derived from WT and U1/KO2, respectively. On the other hand, the values for the maternal and paternal alleles of Zim1 were derived from WT and U1/KO2, respectively. The statistical significance is indicated in the following manner: *, p < 0.05; **, p < 0.01; and ***, p < 0.001.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0224287.g007