Expression of Concern: Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells
Fig 5
NNC 55–0396 dihydrochloride protects SH-SY5Y cells from bupivacaine-induced apoptosis.
Cells were either treated with the indicated concentrations of NNC 55–0396 dihydrochloride or left untreated prior to 1 mM bupivaine treatment for 24 h. Apoptosis rate was measured with flow cytometry (%, mean±SD, n = 3). A: Representative image from the flow cytometric analysis. B: Rates of apoptosis in the different treatment groups. a P<0.05 vs. S group; b P<0.05 vs. S+NNC 100 group; c P<0.05 vs. S+B group; d P<0.05 vs. S+B+NNC 10 group.