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A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats

Fig 1

Glucose metabolism pathways in the liver.

Abbreviations: glucose transporter 2 (GLUT2/Slc2a2); glucokinase phosphofructokinase (Pfkl); pyruvate kinase L/R (Pklr); pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2); pyruvate dehydrogenase kinase, isoenzyme 4 (Pdk4); pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1); pyruvate carboxylase (Pc); glucose-6 phosphatase (G6pc); glycogen synthetase 2 (Gys2); Gys3a; hepatic glycogen synthetase 3 beta (Gsk3b); glucose-6-phosphate dehydrogenase (G6pd); malic enzyme 1 (Me1); o-linked N-acetylglucosamine transferase (OGT).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0222558.g001