Class III β-tubulin expression as a predictor of docetaxel-resistance in metastatic castration-resistant prostate cancer
Fig 3
Kaplan-Meier curve of overall survival (OS) according to class III β-tubulin (βIII-tubulin) positivity.
Proportion of patients that were alive over time in years from the date of pathological diagnosis. Patients were considered to have low expression if the immunostaining was absent (0) or weak (1+) and high expression if staining was moderate (2+) or strong (3+). Log-rank test of equality showed significantly longer survival time in patient with a low βIII-tubulin expression (p = 0.039). Median overall survival was 17.4 months in the high expression group and 19.8 months in the low expression group. The unadjusted HR for OS was 1.69 for the group with a high βIII-tubulin expression (95% CI, 1.02–2.80; p = 0.04).