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Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice

Fig 3

Skeletal muscle functions of mice at 12 weeks of age.

(A) Average daily activity levels analyzed using a voluntary running wheel. Data were expressed as revolutions per day (n = 7). (B) Treadmill running to exhaustion. The average maximum speeds at which mice could not continue running are shown (n = 7). (C) Serum CK levels from sedentary and exercised mice (n = 7–8). **P<0.01 compared with WT mice; ##P<0.01 compared with Emd mice; $$$P<0.001 compared with H222P mice.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0221512.g003