Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target
Fig 5
(A) Interaction of primary hits (ASN.1) is shown in element color ball and stick in surface view within the active pocket of PfPMT. (B) 2D interaction with amino acids within five Å of interaction.(C) Schizonticidal activity (IC50)against growth of Plasmodium falciparum parasite culture.