Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis
Fig 5
Heat map of NETs highlighted proteins.
Heat map of proteome profile of 25 proteins highlight through the combined use of univariate statistical analysis, support vector machine and partial least square discriminant analysis. In heat map, each row represents a protein, and each column corresponds to each condition. Normalized Z-score of proteins abundance are depicted by a pseudo color scale with red indicating positive expression, white equal expression, and blue negative expression compared to each proteins values, whereas the tree dendrogram displays the results of an unsupervised hierarchical clustering analysis placing similar proteome profile values near each other. Visual inspection of the dendrogram and heat map demonstrate the possibility to distinguish among the different condition of NETs induction.