Robust health-score based survival prediction for a neonatal mouse model of polymicrobial sepsis
Fig 3
Health scores at 18 and 24 HPC are related to bacterial load at 24 HPC.
(A) A Kruskal-Wallis comparison of score 18 hours post challenge (HPC) with bacterial load in whole-blood and tissues showed a significant effect (Bonferroni-adjusted p-values < 0.001) indicating score at 18 HPC was related to the bacterial load measured in tissues of the same animals collected 6 hours later (24 HPC). (B) A significant effect was also attained at 24 HPC (Bonferroni-adjusted p-values < 0.001) demonstrating the relationship between health scores and bacterial load across all biological compartments.