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Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice

Fig 3

Loss of Dgki does not affect acute nociception in mice.

(A) The latency to respond to a miniature clothespin attached to the tail. B-D) The latency to respond to immersion of the tail in a bath set to a temperature of -10°C (B), 46.5°C (C), or 49°C (D). E) The rate of response to a light touch with a fluffed-out cotton swab. F) The latency to withdraw the hindpaw from an application of dry ice. G) The latency to lick hindpaw or jump after placement on a 55°C hot plate. The number of mice tested is indicated. Graphs show mean ± SEM.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0217819.g003