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Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

Fig 3

Simple steatosis and biomarker expression begins to resolve upon diet withdrawal for 7 days.

(A) Trichrome stains of representative rats on MCD diet for 1, 2, and 3 weeks then withdrawn to control chow for 1 week. (B) Percentage of MaS, serum ALT (***p<0.001), and liver IL-33 levels on diet (black bars) and after diet withdrawal for 1 week (empty bars). (C) Liver protein expression of biomarker panel after one week diet withdrawal from MCD diet. Representative immunoblots are shown with equal amounts of liver lysate analyzed.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0216242.g003