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Cytokines secreted from bone marrow derived mesenchymal stem cells promote apoptosis and change cell cycle distribution of K562 cell line as clinical agent in cell transplantation

Fig 6

Flow cytometric analysis of bone marrow derived-MSCs co-cultured with K562 cells was performed with a combination of Annexin V-FITC, propidium iodide (PI).

A shift from bottom-right quadrant panel (early apoptosis) to top-right quadrant panel (late apoptosis) and top-left quadrant panel (necrosis) was observed. (A) Unstained cells, (B) Control group and (C) Experimental group.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0215678.g006