High SRC-1 and Twist1 expression predicts poor prognosis and promotes migration and invasion by inducing epithelial-mesenchymal transition in human nasopharyngeal carcinoma
Fig 1
Src-1 and Twist1 is aberrantly up-regulated in nasopharyngeal carcinoma tissues.
(A) the mRNA expression of Src-1 and Twist1 in tumor samples and adjacent normal tissues of the 134 NPC patients was evaluated by qRT-PCR, then relative mRNA expression Log2 (T/N) was calculated. (B) Src-1 or Twist1 expression in tumor samples (T) and paired normal tissues (N) of selected NPC patients was evaluated by western blot. (C, D) Representative images of IHC staining and statistical results for low and high expression of Src-1 or Twist1 in tumor tissues of NPC patients. Scale bars = 50μm. (E) Protein expression of Src-1 and Twist-1 in a panel of nasopharyngeal carcinoma cell lines.