Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
Fig 2
Group comparisons of the relative mRNA levels of the study genes.
Different letters indicate significant differences between the means of the different groups of subjects (p < 0.05; a: Lean NG vs. MO NG; b: Lean NG vs. MO PD; c: MO NG vs. MO PD) according to Mann Whitney U test. Abbreviations: Lean Normoglycemic (Lean NG); Morbid obese normoglycemic (MO NG); Morbid obese prediabetic (MO PD); E2F transcription factor 1 (E2F1); Lipoprotein Lipase (LPL); Sterol regulatory element-binding factor 2 (SREBF2); Stearoyl-CoA desaturase 1 (SCD1); Peroxisome proliferator-activated receptor gamma (PPARG); Interleukin 6 (IL6); Tumor necrosis factor (TNF).