p38 MAPK activity is associated with the histological degree of interstitial fibrosis in IgA nephropathy patients
Fig 6
Microscopic morphological changes in hTECs after treatment with p38 MAPK inhibitor.
(A) Control hTECs show a normal ellipsoid shape and clear contour. (B) Exposure to TGF-β (2 ng/ml) induced bursting and speckled morphological changes in hTECs. (C) Exposure to TGF-β (2 ng/ml) in the presence of p38 MAPK inhibitor (2 μM). (D) Exposure to TGF-β (2 ng/ml) in the presence of p38 MAPK inhibitor (4 μM).