Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause
Fig 2
The SMR plots of novel genes associated with ANM.
(A) The SMR result at AK125462 locus. (B) The SMR result at MSL2 locus. (C) The SMR result at CLSTN3 locus. (D) The SMR result at TRAPPC2L locus. (E) The SMR result at DDX5 locus. (F) The SMR result at CPNE1 locus. In the top plot, black dots represent the p values for the SNPs from the latest GWAS meta-analysis for AAM (Y-axis), diamonds represent the p values for probes from the SMR test. In the bottom plot, the eQTL p values of the SNPs were from the eQTL study (Y-axis).