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Large-scale intrinsic connectivity is consistent across varying task demands

Fig 3

Relationship between task-evoked activation and differences between task-based and resting state FC.

(A) Fisher z-transformed correlation coefficients between pairs of nodes, where only one of the nodes is activated during the motor steady-state condition, are displayed separately for each participant in the form of a histogram (y-axis depicting the number of node pairs in each bin; please note that the range of the y axis differs across individuals due to differences in the total amount of nodes activated during the task). If intrinsic connectivity changes with task activation, then FC should consistently decrease in the task-state, when only one of the nodes is activated, as compared to the resting-state. Although this is true for some participants (e.g. Participants 9 and 10), others show an opposite trend (connectivity increased in the motor condition, see e.g. Participants 1–3). (B) Relationship between number of activated nodes and mean FC for the three task comparisons (motor–pink, visual–blue, visuomotor—green). Note that while a significant main effect of the factor "number of activated nodes" (x-axis) can be observed, no significant interaction between activated nodes and task was found. Error bars indicate standard error of the mean.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0213861.g003