Homeostatic controllers compensating for growth and perturbations
Fig 6
Motif 1 based zero-order integral controller with a transporter (T) generated compensatory flux.
The controller species E is produced by an enzymatic zero-order process from compound M. E is recycled by another zero-order process (with respect to E) but the rate of E-removal is proportional to the concentration of A. Outflow perturbations are represented by the rate r3 = k3⋅A, where k3 is either constant or increases linearly with time.