The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential
Fig 2
Statistical comparison of selected aminoglycosides.
Graphs show average values for at least three independent experiments (open circles) for each aminoglycoside indicated on the y-axis. Error bars indicate the 95% confidence limits for each average. The title of each graph indicates the average measurement or the average calculated ratio. A-C are potency averages from the three readthrough assays; D-F are averages for the three cytotoxicity assays and G-O show the mean ratios between the readthrough and the cytotoxicity assays. All values used for calculating averages can be found in S1 File.