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Multi-locus sequence typing of Treponema pallidum subsp. pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles

Fig 1

Alignment of the different TP0136 allelic variants identified in this study.

Only positions containing nucleotide variants are shown. Only allelic variants identified in this study are shown; for all allelic variants identified so far, see S1 Appendix. A. Nucleotide differences between reference strain TPA SS14 and TPA Nichols in the region characterized using MLST (at coordinates 264–1469 according to the TPANIC_0136; CP004010.2). Coordinates shown above correspond to TPASS_0136 (TPA SS14; CP004011.1) and coordinates shown below correspond to TPANIC_0136 (TPA Nichols; CP004010.2). B. Nucleotide differences in SS14-like allelic variants. Coordinates correspond to TPASS_0136 (TPA SS14; CP004011.1). Allelic variants, which were not described previously, are shown in bold italics. C. Nucleotide differences in Nichols-like allelic variants. Coordinates correspond to TPANIC_0136 (TPA Nichols; CP004010.2).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0201068.g001