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HLA-A*11:01 is associated with levetiracetam-induced psychiatric adverse events

Fig 1

In-silico modeling of the molecular interaction between HLA-A*1101 and LEV.

The LEV molecule was predicted to be docked into the P1 pocket of HLA-A*1101 with relatively higher affinity (5.1 kcal/mol) compared to other HLA-A subtypes. HLA, human leukocyte antigen; LEV, levetiracetam.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0200812.g001