Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection
Fig 5
Comparison of the expression of potential markers of relative mDCs maturation during acute DENV infection.
(A) Representative histogram plots showing maturation markers on mDCs on blood samples from healthy subjects (solid black line, upper panel) and DENV-infected patients (solid black line, lower panel). The shaded grey histograms represent profiles obtained using isotype controls. The relative proportion of CD40 (B), CD80 (C), CD83 (D), and CD86 (E) -expressing mDCs were compared on samples from healthy subjects and DENV-infected patients, DF and DHF patients. The box plot shows the median value (horizontal line in the box). The box and whisker represent 25th to 75th, and 10th to 90th interquartile range, respectively. P values were determined by the Dunn’s post-test after Kruskal-Wallis test for comparison of three groups. (** p < 0.01 and **** p < 0.0001).