Cell-intrinsic regulation of peripheral memory-phenotype T cell frequencies
Fig 5
CD4 TEM and CD8 TEM frequencies and counts (in millions) in spleen in C57BL/6J versus CBA/CaJ (A to D) and BALB/cJ versus SJL/J (E to H). Each dot represents data from one individual mouse (n > 25 per group). CD4 TEM and CD8 TEM frequencies indicate frequencies of TEM compartment (CD44hi CD62Llo) out of total conventional CD4 (CD4+CD25-) and CD8 T cells respectively. Cell counts are expressed in millions. Box plots indicate median and interquartile ranges. Upper whisker extends till the highest value that is within 1.5 times the interquartile range from 3rd quartile. Lower whisker extends till the lowest value that is within 1.5 times the interquartile range from 1st quartile. The p-values obtained by non-parametric tests are as indicated in the panels.