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Daily variation of gene expression in diverse rat tissues

Fig 1

Temporal profiles of genes maintaining circadian rhythmicity in liver, muscle, adipose, and lung.

Upper panel: Heatmaps showing mean expression data from 3 animals sacrificed at the same time point during three consecutive days. Rows represent the different genes, and columns the mean expression values at the different times of the day. From blue to yellow, the expression intensity is increasing. Ordering of genes in the different rows is based on their phase. Heatmap titles indicate the tissue, and the respective bar plots at the top of each subplot represent the 12 h light (white) 12 h dark (grey) periods. The n is for the number of genes found to retain circadian rhythmicity in each tissue Lower panel: Respective phase histograms for the tissues shown in the upper panel. Circular coordinates indicate the time of day and numbers on the nested circles the number of genes. Dark semicircles at the perimeter of the circles indicate the dark phase.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0197258.g001