Acute effects of insulin on circulating natriuretic peptide levels in humans
Fig 1
Circulating insulin and NP concentrations during hyperinsulinemic-euglycemic clamp.
(Panel A) Insulin levels increased from baseline to steady-state (mean increase of 167 μU/ml, p<0.001) in the group as a whole. (Panel B) NT-proANP in the group as a whole decreased from baseline to steady-state (mean decrease of 1933 ng/L, p = 0.01), representing a 9% relative decrease. (Panel C) NT-proBNP did not change significantly from baseline to steady-state in the group as a whole (mean change -0.45 ng/L, p = 0.40).