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Epileptiform activity during inert gas euthanasia of mice

Fig 2

Demographics of epileptiform activity.

(A) Prevalence of epileptiform events resulting from exposure to each gas. Note that electrophysiological epileptiform activity was exhibited by CO2; however, only one out of six animals demonstrated physical signs of epileptiform activity. Only Xe did not result in any epileptiform activity. (B) Duration of epileptiform events. CO2 produced the shortest epileptiform events, and He the longest. There was no difference between N2 and Ar.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0195872.g002