Using hydrodynamic focusing to predictably alter the diameter of synthetic silk fibers
Fig 2
A biomimetic silk spinning system designed from Nephila clavipes and Bombyx mori silk glands.
Schematic outlining the zones of fiber production in silkworms and spiders. Notice that the microfluidic system described in this manuscript mimics each zone. Zone 1 (Z1) mimics protein creation and beginning flow inlet to the system. Zone 2 (Z2) mimics the lumen of the gland through protein storage and beginning of biochemical stimulus. Zone 3 (Z3) mimics the duct region providing pH and ionic gradients as well as mechanical shear through hydrodynamic focusing.