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TGF-β1/CD105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels

Fig 3

Spreading of hCDC to HyA matrices after 3 days.

Actin stain of hCDC encapsulated in (A) HyA, (B) HyA-TGF-β1 and (C) HyA-TGF-β1/CD105 Ab blocking. (D) Quantification of cell area shows that TGF-β1 significantly enhances the spreading of hCDC, but that this effect can be abrogated by pre-incubation with CD105 antibody. Data represents mean ± SD (n = 3). Analysis performed using one-way ANOVA, p < 0.05. * denotes statistical significance. Scale Bar = 100 μm.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0194679.g003