Comparison of secretome from osteoblasts derived from sclerotic versus non-sclerotic subchondral bone in OA: A pilot study
Fig 1
Gene expression by NSC or SC osteoblasts.
(A) less secreted proteins (B) more secreted proteins. The mRNA copy numbers were normalized against the corresponding copy number of HPRT mRNA and results are showed as the SC relative to NSC gene expression (mean ± SEM of five independent experiments performed with bone biopsy coming from different donors). In each experiment, each experimental condition was performed in duplicate. P: comparisons of mean values between NSC and SC were performed by unpaired t-test. Dotted blue line in each gene represents the result obtained with MS/MS in secretome with the corresponding protein.